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Prof.dr. Wiro Niessen
| Speaker: |
Prof.dr. Wiro J. Niessen (Erasmus Universiteit Rotterdam)
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| Date: |
Wednesday May 16, 2007
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| Title: |
Vascular image
analysis: From vessel enhancement to intravascular
interventions
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Abstract
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Atherosclerosis,
a localized disease of the vessel wall caused by systemic risk factors,
is the main cause of morbidity and mortality in the western world.
There is large evidence that the risk of clinical events depend more on
atherosclerotic plaque composition, than on luminal morphology.
Consequently, there is not only strong interest in imaging technologies
that enable quantitative analysis of the vessel lumen, but also in
detection and characterization of the atherosclerotic vessel wall.
Imaging of the vessel lumen has been clinically available for a number
of decades. Currently, a number of imaging techniques that are capable
of visualizing the vessel wall are receiving increasing attention.
Intravascular ultrasound (IVUS) is well-established in coronary
imaging, but is invasive. CT and MRI have great potential for
non-invasive imaging of atherosclerotic plaque, but have different
spatial and temporal resolution, and different capacities in
visualizing plaque content.
Emerging imaging technologies provide information related to
biophysical and biochemical plaque properties. Owing to these different
qualities, vessel wall analysis based on multimodal imaging data would
be highly desirable.
In this talk, image processing techniques will be presented to enable
analysis of both the vessel lumen and wall. With respect to vessel
lumen analysis, vessel enhancement and quantification for improved
diagnosis and therapy planning will be discussed. Subsequently,
techniques for the integrated analysis of the vessel wall based on
different vascular imaging modalities will be shown. Finally,
techniques to relate pre- and intra-operative imaging data, for optimal
guidance in minimally invasive vascular interventions, are presented.
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